• br Case report A year old man who

  2018-11-02

  

  Case report A 23-year-old man, who denied any systemic disease, history of recent trauma, or history of urinary tract infection, noted a right testicular mass for more than 5 years. A physical examination showed a hard mass, measuring 2 cm × 3 cm, without pain and with a tender sensation. All lab

• A limitation of molecular assays for detection of protozoan

  2018-11-02

  

  A limitation of molecular assays for detection of protozoan oocysts in produce is the inability to distinguish live from dead organisms, making it difficult to interpret the results and determine the significance of positive results with respect to the risk posed by the contamination. However, popul

• Introduction The intestinal tract of adult

  2018-11-02

  

  Introduction The intestinal tract of adult carries 1–2kg of microbes. It is a common knowledge that pathogenic microbes could cause infectious diseases such as diarrheal, while others are associated with inflammatory and allergic diseases [1–3]. On the other hand, the majority of the gut microbes

• In this study we investigated

  2018-11-02

  

  In this study, we investigated whether transgenic selection could help to enrich low-purity populations that commonly result from pMN differentiation protocols. We generated a new heterozygous “knock in” mouse ESC line (P-Olig2) where the protein-coding region in one allele of Olig2 was replaced wit

• br Results br Discussion One way to

  2018-11-02

  

  Results Discussion One way to obtain good-quality iPSCs is to screen many iPSCs lines derived from the same patient tissue for genomic aberrations. However, given the high number of cell divisions, compounded by the increased rate of genotoxicity during reprogramming (Banito et al., 2009; Gonz

• br Materials and methods br Results br Discussion Characteri

  2018-11-02

  

  Materials and methods Results Discussion Characterization of the karyotypically abnormal cells and culture adaptation process is important for stem cell biology and can provide valuable insights into the mechanisms regulating transformation of cells towards malignant fate. In this study we

• In summary this study revealed the unexpected

  2018-11-02

  

  In summary, this study revealed the unexpected capacity of Sox2 for converting reactive glial cells into induced DCX+ neurons in the injured cerebral cortex. Our work highlights the potential of NG2 glia as cellular candidates for de novo generation of new neurons in the cerebral cortex, a heat shoc

• Rejection might also have occurred as iPSC

  2018-11-02

  

  Rejection might also have occurred as iPSC-CMs might fail to suppress recipient NK chemicals in MHC-matched transplantation. MHC class I molecules such as MHC-E, which are expressed on almost all cells in the body, bind to receptors on NK cells to inhibit cytotoxic activity and, following the immun

• br Results br Discussion The MSC secretome is being explored

  2018-11-02

  

  Results Discussion The MSC secretome is being explored in pre-clinical and clinical trials as one of the primary mediators of cardiovascular repair via immunomodulatory effects (Ranganath et al., 2012). However, to date, approaches have not met with success as initially hoped. The immunomodula

• Although due to limitations of the current tools and technic

  2018-11-02

  

  Although, due to limitations of the current tools and technical challenges, we could not perform direct manipulation of the 11 miRNAs to rescue/inhibit neurogenesis in vivo, we demonstrated that most of these miRNAs are expressed in adult-born hippocampal neurons, and consequently depleted upon the

• The results of the Western blot analysis reveal

  2018-11-02

  

  The results of the Western blot analysis reveal that downregulated expression of the examined proteins is observed in all transgenic 5×FAD mice, but is more pronounced for 6-month-old mice (nos. 6 and 8), especially for STIM2. In 4-month-old transgenic 5×FAD mice, STIM2 expression (2 and 4) was down

• Calculation scheme According to Buckingham s theory for a

  2018-11-02

  

  Calculation scheme. According to Buckingham\'s theory for a system of two polar components, the following relationships hold true: where ε is the dielectric permittivity; n is the refractive index; V is the molar volume, V= ( is the specific volume; М is the molecular weight); х is the molar fract

• These results confirm that group position theory a sociologi

  2018-11-02

  

  These results confirm that group position theory, a sociological social psychological theory that explains negative emotions arising from intergroup relations, can be applied to the study of affect-related health behaviors and outcomes. In his original articulation of group position theory, Blumer a

• Hypocretinergic activation during REM sleep is likely relate

  2018-11-02

  

  Hypocretinergic activation during REM sleep is likely related to the activation that occur during certain patterns of somatomotor activity [50]. Although motor output is inhibited at the motoneuron level during REM sleep, supraspinal motor systems are very active during this state [60–62]. In fact,

• Spearman rank order correlations between

  2018-11-02

  

  Spearman rank-order correlations between PSG and actigraphy measures are presented in Table 3. Positive correlations were noted between PSG and both wrist actigraphy sleep summary measures (original: r=0.24–0.53, all pCy3.5 hydrazide cluster near the horizontal line, indicating small differences, an

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