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The ubiquitously expressed FGF is the prototypic member
2018-10-26
The ubiquitously expressed FGF2 is the prototypic member of the paracrine group of human FGFs (Beenken and Mohammadi, 2009). Its endogenous expression is regulated at multiple levels including the alternative translation of polypeptides that eventually differ in size (18–34kDa), domain structure and
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TIC10 Supplier An adequate regenerative outcome depends on
2018-10-26
An adequate regenerative outcome depends on the presence of exogenous and/or endogenous stem cells, or on the existence of a pool of constantly cycling parenchymal cells. Replicating myocytes are small in size and mononucleated, suggesting that they might derive from: a) activation and differentiati
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Taken together these findings indicate
2018-10-26
Taken together, these findings indicate that basal-to-luminal differentiation can occur in prostate organogenesis, pathogenesis, and ex vivo assays, but rarely during normal tissue homeostasis. Thus, it has been unclear to what extent the plasticity of endogenous adult prostate basal discover this i
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In addition recent findings indicate that
2018-10-26
In addition, recent findings indicate that the majority of in vitro expanded cells undergo apoptosis upon implantation (Stegen et al., 2016). A cause may be the need to instantly adjust to a compromised environment, since current culture conditions represent a rather non-physiological and abundant n
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In this study we showed that Lxn
2018-10-26
In this study, we showed that Lxn orexin antagonist in vivo leads to increased numbers of HSCs, HPCs, and all blood cell lineages. Loss of Lxn enhanced long-term repopulating capacity and survival of HSCs. Mechanistically, gene array analysis showed that genes involved in cell-cell and cell-matrix
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Several approaches have been developed
2018-10-26
Several approaches have been developed to differentiate hESCs into pancreatic progenitor membrane transporter (minimum of stage 4 [S4] of differentiation), which undertake the final stages of glucose-responsive β-cell differentiation in vivo (Bruin et al., 2013; D\'Amour et al., 2006; Kelly et al.,
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The prevalence of mental illness alcoholism and sleep distur
2018-10-26
The prevalence of mental illness, alcoholism, and sleep disturbances are shown in Table 2. The prevalence of mental illness (serious mental illness and mild-moderate mental illness) increased during the follow-up p38 inhibitors (P Discussion This study showed the long-term trends of psychological
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While several recent studies have
2018-10-26
While several recent studies have shown positive correlations between FHS coverage at the mek inhibitor level and child health outcomes (Brandao, Gianini, Novaes, & Goldbaum, 2011; Macinko et al., 2007; Rasella, Aquino, & Barreto, 2010a, 2010b; Reis, 2014; Rocha & Soares, 2010), the existing litera
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br Recommendations The science of
2018-10-26
Recommendations The science of measuring and improving the built environment related to nutrition, activity and obesity is inherently multidisciplinary. Research to assess and change built environments related to obesity, activity and nutrition has increased many interdisciplinary collaborations.
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chemokine receptor antagonist Apart from positive health eff
2018-10-26
Apart from positive health effects, social support seems to be equally beneficial for well-being at work. In particular, social support has been shown to reduce job stress (Beehr, Farmer, Glazer, Gudanowski & Nadig Nair, 2003; Oginska-Bulik, 2005), to enable people to cope better with or provide che
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br Acknowledgements This work was supported by NIH
2018-10-26
Acknowledgements This work was supported by NIH grants 1R01MD006064 and 1R21HD066312 (Dr. Osypuk, PI), and the Minnesota Population Center grant P2C HD041023. Funders did not have any role in design or conduct of the study; collection, management, analysis, and interpretation of the data; or prep
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The Langmuir isotherm suggests monolayer adsorption
2018-10-26
The Langmuir isotherm suggests monolayer adsorption on a homogeneous surface with a finite number of adsorption sites and without any interaction between the adsorbed molecules (Acharya et al., 2009a, 2009b). The Langmuir equation relates solid phase adsorbate concentration (qe), the uptake, to the
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The effect of the Rw composition on the Vs and
2018-10-26
The effect of the Rw composition on the Vs and Vp in the system Mg2SiO4–Fe2SiO4 at a typical P-T condition of the lower part of the MTZ (21 GPa and 1800 K) is shown in Fig. 5. The calculation was done with the data listed in Table 5. The composition effect is still very prominent: when the Rw change
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br Conflict of interest br Introduction
2018-10-26
Conflict of interest Introduction Methods Results Within the OSAHS group, d was significantly lower in the afternoon 1.705±0.033 than the morning 1.737±0.042 (Fig. 1) (p Discussion This is the first study to investigate dynamically and quantify the arrangement and mechanical properties
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br Introduction Glucose is the
2018-10-26
Introduction Glucose is the most widely distributed monosaccharide in nature and plays a very important role in the fields of life science [1], biology [2–4], clinical analysis [5], and food industry [6]. As a major source of ezh2 pathway for living cells, the glucose acts as an indispensable me
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