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The current study has investigated the cell death pathway
2018-11-06

The current study has investigated the cell death pathway(s) utilized by mESCs in response to etoposide (ETO), a topoisomerase II poison that indirectly induces DNA double strand breaks (DSBs) (Baldwin and Osheroff, 2005). The data show that ETO not only induces cell death with hallmarks of both PCD
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The goals of this study were to
2018-11-06

The goals of this study were to evaluate if human fetal gallbladder contains a clonogenic candidate stem cell population and compare its phenotypic and expression profiles to those of fetal IHBD cells. The evaluation of human fetal gallbladder stem Amyloid Beta-peptide (25-35) would have important
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br Introduction The human gallbladder mainly functions
2018-11-06

Introduction The human gallbladder mainly functions to concentrate and store bile, and like anatomically close-by organs—the liver and the pancreas—is derived from the foregut endoderm during embryonic development (Spence et al., 2009). The extrahepatic biliary tree (comprising extrahepatic bile
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We identified a number of CD markers
2018-11-06

We identified a number of CD markers that are expressed in both osteoprogenitor and adipoprogenitor azd2171 and thus can be employed as core markers of the BMSCs phenotype. Our data corroborate previous studies that employed alternative technologies to identify markers for multipotent BMSCs. Compari
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Creating a genetically diverse set
2018-11-06

Creating a genetically diverse set of differentiated buy Tovok for the purposes of phenotype-genotype studies would have great value in pharmacogenomics, a field that has relied primarily on EBV-transformed lymphoblastoid cell lines (Moen et al., 2012; Wheeler and Dolan, 2012; Welsh et al., 2009). T
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Another important advantage of this technical report is the
2018-11-06

Another important advantage of this technical report is the successful application of dCas9 activators for validation of PAX7 knock-in reporter Cy3.5 hydrazide manufacturer (Cheng et al., 2013). By design and assembly of site-specific dCas9 activators for PAX7 in human iPS cells, these activators h
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br Experimental Procedures br Acknowledgments br Introductio
2018-11-06

Experimental Procedures Acknowledgments Introduction There are three distinct and differentially regulated stages in mammary gland development (embryonic, pubertal, and pregnancy/lactation), and the most substantial remodeling is postnatal (Gjorevski and Nelson, 2011). The mammary epitheliu
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Our studies show that only a subpopulation of
2018-11-06

Our studies show that only a subpopulation of hESCs at the top of the hierarchy possesses an extensive capacity for self-renewal. Polanco et al. recently showed that LCL161 in this compartment could reestablish the continuum of cell states seen in unfractionated cultures (Polanco et al., 2013). Usi
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LY2874455 Importantly we found that both HIF factors nonredu
2018-11-06

Importantly, we found that both HIF factors nonredundantly regulate the morphology and behavior of primary mesenchymal progenitors: in the absence of HIFα expression PαS+ mesenchymal progenitors show impaired proliferation, colony forming ability, and differentiation and acquire an elongated and mot
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Introduction of the lentiviral vector LV platform has
2018-11-05

Introduction of the lentiviral vector (LV) platform has spurred applications of gene therapy based on the transplantation of ex-vivo-engineered, autologous hematopoietic stem and progenitor cells (HSPCs) (Naldini, 2015). Recent clinical trials for patients affected by primary immunodeficiencies, hem
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In this regard equivalent circuit modeling provides
2018-11-05

In this regard, equivalent circuit modeling provides a means to extract the contribution of individual components (i.e., cell, substrate, and cell culture medium) from overall impedance changes. There were several studies that attempted to characterize stem cell differentiation via monitoring impeda
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The problem of reconstruction of a
2018-11-05

The problem of reconstruction of a full 2D function from a set of projections is known as “tomography problem”, and has been extensively studied for medicine and plasma physics applications, and the corresponding mathematical methods could be used in our case. Though, a specific feature of the data
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An approximate solution is sought in the form of
2018-11-05

An approximate solution is sought in the form of an output of an artificial neural network of the given architecture: whose weights are determined when minimizing the error functional and for our case, F(x, y, α) = –α(y – cosx). Test points () are chosen to be random and distributed uniformly
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There are currently several known mechanisms for generating
2018-11-05

There are currently several known mechanisms for generating terahertz radiation, based on impurity-assisted transitions of charge carriers in semiconductors and semiconductor nanostructures. For example, terahertz ML216 was observed during optical transitions of nonequilibrium charge carriers invo
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br Conclusion Despite its limitations this research addresse
2018-11-05

Conclusion Despite its limitations, this research addressed several aspects of fall prevention and rehabilitation. First, it BDS I showed that frailty and falls were closely interrelated; falls may be a reliable indicator of frailty and may be systematically researched by professionals as a scr
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