• Although due to limitations of the current tools and technic

  2018-11-02

  

  Although, due to limitations of the current tools and technical challenges, we could not perform direct manipulation of the 11 miRNAs to rescue/inhibit neurogenesis in vivo, we demonstrated that most of these miRNAs are expressed in adult-born hippocampal neurons, and consequently depleted upon the

• The results of the Western blot analysis reveal

  2018-11-02

  

  The results of the Western blot analysis reveal that downregulated expression of the examined proteins is observed in all transgenic 5×FAD mice, but is more pronounced for 6-month-old mice (nos. 6 and 8), especially for STIM2. In 4-month-old transgenic 5×FAD mice, STIM2 expression (2 and 4) was down

• Calculation scheme According to Buckingham s theory for a

  2018-11-02

  

  Calculation scheme. According to Buckingham\'s theory for a system of two polar components, the following relationships hold true: where ε is the dielectric permittivity; n is the refractive index; V is the molar volume, V= ( is the specific volume; М is the molecular weight); х is the molar fract

• These results confirm that group position theory a sociologi

  2018-11-02

  

  These results confirm that group position theory, a sociological social psychological theory that explains negative emotions arising from intergroup relations, can be applied to the study of affect-related health behaviors and outcomes. In his original articulation of group position theory, Blumer a

• Hypocretinergic activation during REM sleep is likely relate

  2018-11-02

  

  Hypocretinergic activation during REM sleep is likely related to the activation that occur during certain patterns of somatomotor activity [50]. Although motor output is inhibited at the motoneuron level during REM sleep, supraspinal motor systems are very active during this state [60–62]. In fact,

• Spearman rank order correlations between

  2018-11-02

  

  Spearman rank-order correlations between PSG and actigraphy measures are presented in Table 3. Positive correlations were noted between PSG and both wrist actigraphy sleep summary measures (original: r=0.24–0.53, all pCy3.5 hydrazide cluster near the horizontal line, indicating small differences, an

• A complete polysomnographic evaluation was performed using a

  2018-11-01

  

  A complete polysomnographic evaluation was performed using a digital system (EMBLA® S7000, Embla Systems, Inc., Broomfield, CO, USA) according to the manual of the American Academy of Sleep Medicine (2007) [8]. The hypopnea stage was defined according to the recommended rule (AASM, 2007) [8]. CBCT

• br Conflict of interest br Acknowledgment

  2018-11-01

  

  Conflict of interest Acknowledgment This work was supported by the Hong Kong Research Grant Council (RGC), Grant Ref 610412 and CityU 11200814. Introduction Graphene continues to attract attention for its application to biosensing, particularly the detection of trace concentrations of macr

• De esta forma se incrementa la

  2018-11-01

  

  De esta forma, se incrementa la csf1r monetaria pero no la oferta monetaria, pues el multiplicador bancario deja de funcionar (McCulley, 2013); la liquidez creada por el Banco Central no es reintegrada el circuito de la circulación monetaria por medio de la concesión de nuevos créditos, sino que pe

• br La Comunidad Econ mica Europea

  2018-11-01

  

  La Comunidad Económica Europea Antes de que se concretara un auténtico proyecto y que se volviera un objetivo preciso de la política gubernamental de los países europeos, la idea europea se limitaba LY294002 los escritos de filósofos y escritores. La perspectiva de los Estados Unidos de Europa, s

• As opposed to schwannomas other driver

  2018-11-01

  

  As opposed to schwannomas, other driver mutations have been identified in meningioma, but those are mutually exclusive of Merlin (Clark et al., 2013). In order to keep the genetic background consistent with schwannoma, we analysed only Merlin-deficient WHO grade I meningiomas. Comparative functional

• Autophagy enables cancer cell survival

  2018-11-01

  

  Autophagy enables cancer cell survival by maintaining energy production, which can lead to therapeutic resistance (). Several preclinical studies showed that clinically relevant doses of radiation directly promote autophagy in cancer cells and inhibition of autophagy can restore chemosensitivity and

• br Specifications Table br Data br Experimental

  2018-11-01

  

  Specifications Table Data Experimental design, materials and methods Acknowledgements T.S.S. is grateful to Nadathur Estates for their support of all the breast cancer research activities at SJRI since 2008. We thank the Department of Biotechnology for the DBT-BBI grant (No: BT/PR13926/M

• Regarding VS connectivity the progressively decreasing VS iF

  2018-11-01

  

  Regarding VS connectivity, the progressively decreasing VS iFC with age in insula and dACC suggests that VS–insula and VS–dACC circuits occupy an important position in the neural (and thus behavioral) repertoire of youths. In other words, based on the putative notion that an iFC network represents t

• These opposing findings may actually provide a useful concep

  2018-11-01

  

  These opposing findings may actually provide a useful conceptual foil, and suggest that provided the incentive task for fMRI features either: (a) very engaging visual stimuli (such as casino iconography, social cartoons or driving simulations), (b) decisions between rewarding options, or (c) peers p

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