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br Pathophysiology of premature ovarian failure By the
2020-12-21
Pathophysiology of premature ovarian failure By the age of 40 years, 1% of women spontaneously develop POF [18]. The normal menopause occurs at an average age of 51 years [19] and results from ovarian follicle depletion [20], whereas POF is a heterogeneous disorder and can result from either foll
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br Experimental Procedures br Acknowledgments
2020-12-21
Experimental Procedures Acknowledgments Introduction Bisphenol A (BPA), 2,2-bis (4-hydroxyphenyl) propane, is widely used to manufacture consumer products including food and beverage containers (Vandenberg et al., 2007). It can be accumulated in human body via leaching from the polymers in
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Another important new result that
2020-12-18
Another important new result that has expanded the range of functions of iPLA2-VIA in physiology and pathophysiology is its implication in macrophage polarization under stimulation conditions. Ashley et al. [129] described in peritoneal macrophages from Pla2g6−/− mice that the absence of iPLA2-VIA f
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Some authors rather than using magnetic NPs
2020-12-18
Some authors, rather than using magnetic NPs as heat sources, have enhanced the activity of the linked enzymes by applying low frequency AMF. Magnetic energy is converted into a rotational motion of the enzyme-particle system that increase the collision rate with the substrate [14], [15], or trigger
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br Results br Discussion It
2020-12-18
Results Discussion It has been thought that commitment to the plasma cell fate begins while D-(-)-Salicin are still in the GC (Suan et al., 2017, Victora and Nussenzweig, 2012), but the main obstacle to test this model and, if correct, to clarify how the plasma cell-prone GC cells develop has
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Lymphocyte mobility and homing is modulated by the chemoattr
2020-12-18
Lymphocyte mobility and homing is modulated by the chemoattractant receptor subfamily of G protein-coupled receptors (GPCRs) (Campbell et al., 2003, Rot and von Andrian, 2004). B cell migration and position are controlled to a large extent by the lymphoid chemokines CXCL13, CXCL12, CCL19, and CCL21
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br Acknowledgment This work was supported by the Estonian Sc
2020-12-18
Acknowledgment This work was supported by the Estonian Science Foundation (Grant ETF8862). Introduction In higher eukaryotes ionizing-radiation (IR) induced DNA double-strand breaks (DSB) are primarily repaired by the non-homologous end joining (NHEJ) pathway [1]. Ku, a heterodimeric protein
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Db model cells showed various
2020-12-18
Db model cells showed various aberrant phenotypes that seemed to reflect the pathological abnormalities found under diabetic conditions. First, in Db model cells after insulin stimulation, we found the inhibition of the transcriptional repression of the gluconeogenic genes, PCK1 and G6PC, and aberra
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Eleutherococcus senticosus Rupt Maxim Maxim is
2020-12-18
Eleutherococcus senticosus (Rupt. & Maxim.) Maxim is a shrub belonging to the Araliaceae, which is commonly distributed in China, Korea, Japan and Russia. It has been traditionally used as folk medicine for the treatment of rheumatism, diabetes, and hepatitis (Nan et al., 2004). Recent phytochemical
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Telbivudine sale It was demonstrated that the addition of fo
2020-12-18
It was demonstrated that the addition of 10-fold excess of α-synuclein without modifications (with respect to the molar concentration of tetrameric GAPDH) leads to partial inactivation of GAPDH after 1-h incubation by 20% (Fig. 4, curve 2) in Telbivudine sale to insignificant decrease of the specif
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Introduction Cysteinyl leukotrienes CysLTs LTC
2020-12-17
Introduction Cysteinyl leukotrienes (CysLTs), LTC4, LTD4 and LTE4, are 5-lipoxygenase pathway metabolites of arachidonic Benzoylmesaconitine receptor and deeply involved in bronchial asthma via activation of CysLT1 receptors [1], [2]. Specific CysLT1 receptor antagonists, including pranlukast [3],
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In addition to its HEAT repeats CRM also possesses
2020-12-17
In addition to its HEAT repeats, CRM1 also possesses a C-terminal extension (C-extension, residues 1032–1071), composed of a helix (C-helix) followed by a short stretch of residues (C-tail). In the absence of Ran, the C-extension adopts a conspicuous conformation that bridges across the ring-shaped
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Both anxiogenic and antinociceptive effects
2020-12-17
Both anxiogenic and antinociceptive effects produced by CRF seem to be selective for the CRF1 receptor, since intra-dPAG microinjection of ASV 30, a CRF2 receptor antagonist, altered neither the anxiety nor the antinociception response. Intra-dPAG ASV 30 was also unable to prevent the anxiogenic (ob
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br Bipartite graph br Algorithm for CFC br Error detection
2020-12-17
Bipartite graph Algorithm for CFC Error detection rate and overhead evaluation Test results and discussion For verifying the proof in Ranolazine receptor from the perspective of practice, this section brings tests and analysis based on the onboard computer (OBC) of the in-service ZDPS-1
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The assessment process is even
2020-12-17
The assessment process is even more difficult when Commercial-Off-The-Shelf (COTS) components – whose internals are partially or totally unknown – come into play. COTS are being increasingly used by the industry to reduce costs and to shorten development (and possibly deployment) time. However, sinc
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