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This study has limitations First the four
2018-11-05
This study has limitations. First, the four studies were designed independently and involved different methods for recording toxicity. Endpoints needed harmonizing and the approach might be sub-optimal, but serves as a useful guide for future radiogenomics studies involving multiple cohorts. Althoug
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One thing that we learned in the presented ZIKV vaccine
2018-11-05
One thing that we learned in the presented ZIKV vaccine studies is that the yield of production of the ZIKV envelope E subunit protein was very low in the current format. This finding, also confirmed by a recently published ZIKV vaccine study (Larocca et al., 2016), is similar to what was previously
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Antiretroviral drugs have also been
2018-11-05
Antiretroviral drugs have also been a focus of attention for this purpose. A differential impact of drug ion channels and individual drugs has been the hypothesis for some analysis of randomized clinical trials. Information on the impact of different ART regimens on inflammatory biomarkers linked wi
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Helminth immunotherapy is also being
2018-11-05
Helminth immunotherapy is also being evaluated as a therapy for MS, with varying success. So far, clinical trials with TSO in the context of MS have demonstrated modest to no clinical improvement (Wolff et al., 2012). However, in a prospective study where MS patients were enrolled during remission,
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Ependymal cell derived astrocytes are located at
2018-11-05
Ependymal cell-derived astrocytes are located at the core of the lesion site, while resident astrocytes proliferate and are recruited at the border of the lesion site after spinal cord injury (Barnabe-Heider and Frisen, 2008; Burda and Sofroniew, 2014). It was demonstrated that ageing changes the as
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br Conflict of interest br Contribution details br Acknowled
2018-11-05
Conflict of interest Contribution details Acknowledgement This study was supported by a financial grant from Swami Rama Himalayan University. We are also thankful to Dr. Judith Owens to allow us to use the Hindi version of CSHQ. Introduction Although considered the gold standard method
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DMXAA br Conclusion We designed and manufactured a portable
2018-11-05
Conclusion We designed and manufactured a portable smartphone holder and DMXAA LFA strip to produce a smartphone-based measurement system. Salivary cortisol concentration serves as a biomarker of psychological stress. Because physiological cortisol is secreted in a circadian rhythmic manner, the
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Our results agree with the strategy of
2018-11-03
Our results agree with the strategy of shortening the duration of dual NS5B/NS5A combined therapy to 8weeks, but based on an on-treatment response predictor rather than a baseline variable. This supports the findings of many other studies for the validity of early on-treatment response kinetics as a
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Findings from the most recent Global Burden of
2018-11-03
Findings from the most recent Global Burden of Disease study, published in October 2016 in , show that in 2015, the mean life expectancy worldwide had reached roughly 72years. This is an increase of 10years since 2000, largely attributed to improvements in childbirth-associated and infant mortality,
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br Data This data article presents the protein
2018-11-03
Data This data article presents the protein level of HO-1 (Fig. 1) and CD200 (Fig. 2) secreted by BM-MSCs, WJ-MSCs and AT-MSCs in the absence (constitutive) or in the presence of activated T-cells (co-culture). Experimental design, materials and methods Acknowledgements We gratefully ackno
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br Acknowledgements This work is
2018-11-03
Acknowledgements This work is supported by National Natural Science Fund of China, China (Grant no. 61375079). Data Data shared in this article concern the validation of a model for evaluating the performances of a post-combustion CO2 capture membrane system. Data consist of molar fractions o
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mglur br Data The data in this data article has
2018-11-03
Data The data in this data article has been gathered under a ‘Direct geothermal mglur research and demonstration project’ run under the Sustainable Energy Pilot Demonstration (SEPD) program funded by the state government of Victoria, Australia. Under this project, around 20 buildings were select
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Finally initial studies examining the
2018-11-03
Finally, initial studies examining the relationship between ISVRT and NS-398 activation correlated overall subject ISVRT measures with task-related average neural responses across individuals (e.g., Bellgrove et al., 2004). While these studies shed light on the overall relationship between a subject
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The etiology of CAD is still not
2018-11-03
The etiology of CAD is still not well understood. Evidence suggests that CAD is a delayed type hypersensitivity reaction to endogenous photoinduced antigens. The action spectrum for CAD has been shown to resemble that for sunburn in normal individuals, for which the chromophore is considered to be D
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Adipocytes are described as newly introduced members of the
2018-11-03
Adipocytes are described as newly introduced members of the immune system, as they release cytokines such as interleukin 6 and TNF-α in addition to adipokines such as irisin, adiponectin, and leptin. Discovered by Boström et al, irisin is made up of 112 amino acids, and is synthesized in the muscul
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