• br Results br Discussion One way to

  2018-11-02

  

  Results Discussion One way to obtain good-quality iPSCs is to screen many iPSCs lines derived from the same patient tissue for genomic aberrations. However, given the high number of cell divisions, compounded by the increased rate of genotoxicity during reprogramming (Banito et al., 2009; Gonz

• br Materials and methods br Results br Discussion Characteri

  2018-11-02

  

  Materials and methods Results Discussion Characterization of the karyotypically abnormal cells and culture adaptation process is important for stem cell biology and can provide valuable insights into the mechanisms regulating transformation of cells towards malignant fate. In this study we

• In summary this study revealed the unexpected

  2018-11-02

  

  In summary, this study revealed the unexpected capacity of Sox2 for converting reactive glial cells into induced DCX+ neurons in the injured cerebral cortex. Our work highlights the potential of NG2 glia as cellular candidates for de novo generation of new neurons in the cerebral cortex, a heat shoc

• Rejection might also have occurred as iPSC

  2018-11-02

  

  Rejection might also have occurred as iPSC-CMs might fail to suppress recipient NK chemicals in MHC-matched transplantation. MHC class I molecules such as MHC-E, which are expressed on almost all cells in the body, bind to receptors on NK cells to inhibit cytotoxic activity and, following the immun

• br Results br Discussion The MSC secretome is being explored

  2018-11-02

  

  Results Discussion The MSC secretome is being explored in pre-clinical and clinical trials as one of the primary mediators of cardiovascular repair via immunomodulatory effects (Ranganath et al., 2012). However, to date, approaches have not met with success as initially hoped. The immunomodula

• Although due to limitations of the current tools and technic

  2018-11-02

  

  Although, due to limitations of the current tools and technical challenges, we could not perform direct manipulation of the 11 miRNAs to rescue/inhibit neurogenesis in vivo, we demonstrated that most of these miRNAs are expressed in adult-born hippocampal neurons, and consequently depleted upon the

• The results of the Western blot analysis reveal

  2018-11-02

  

  The results of the Western blot analysis reveal that downregulated expression of the examined proteins is observed in all transgenic 5×FAD mice, but is more pronounced for 6-month-old mice (nos. 6 and 8), especially for STIM2. In 4-month-old transgenic 5×FAD mice, STIM2 expression (2 and 4) was down

• Calculation scheme According to Buckingham s theory for a

  2018-11-02

  

  Calculation scheme. According to Buckingham\'s theory for a system of two polar components, the following relationships hold true: where ε is the dielectric permittivity; n is the refractive index; V is the molar volume, V= ( is the specific volume; М is the molecular weight); х is the molar fract

• These results confirm that group position theory a sociologi

  2018-11-02

  

  These results confirm that group position theory, a sociological social psychological theory that explains negative emotions arising from intergroup relations, can be applied to the study of affect-related health behaviors and outcomes. In his original articulation of group position theory, Blumer a

• Hypocretinergic activation during REM sleep is likely relate

  2018-11-02

  

  Hypocretinergic activation during REM sleep is likely related to the activation that occur during certain patterns of somatomotor activity [50]. Although motor output is inhibited at the motoneuron level during REM sleep, supraspinal motor systems are very active during this state [60–62]. In fact,

• Spearman rank order correlations between

  2018-11-02

  

  Spearman rank-order correlations between PSG and actigraphy measures are presented in Table 3. Positive correlations were noted between PSG and both wrist actigraphy sleep summary measures (original: r=0.24–0.53, all pCy3.5 hydrazide cluster near the horizontal line, indicating small differences, an

• A complete polysomnographic evaluation was performed using a

  2018-11-01

  

  A complete polysomnographic evaluation was performed using a digital system (EMBLA® S7000, Embla Systems, Inc., Broomfield, CO, USA) according to the manual of the American Academy of Sleep Medicine (2007) [8]. The hypopnea stage was defined according to the recommended rule (AASM, 2007) [8]. CBCT

• br Conflict of interest br Acknowledgment

  2018-11-01

  

  Conflict of interest Acknowledgment This work was supported by the Hong Kong Research Grant Council (RGC), Grant Ref 610412 and CityU 11200814. Introduction Graphene continues to attract attention for its application to biosensing, particularly the detection of trace concentrations of macr

• De esta forma se incrementa la

  2018-11-01

  

  De esta forma, se incrementa la csf1r monetaria pero no la oferta monetaria, pues el multiplicador bancario deja de funcionar (McCulley, 2013); la liquidez creada por el Banco Central no es reintegrada el circuito de la circulación monetaria por medio de la concesión de nuevos créditos, sino que pe

• br La Comunidad Econ mica Europea

  2018-11-01

  

  La Comunidad Económica Europea Antes de que se concretara un auténtico proyecto y que se volviera un objetivo preciso de la política gubernamental de los países europeos, la idea europea se limitaba LY294002 los escritos de filósofos y escritores. La perspectiva de los Estados Unidos de Europa, s

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