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Smoking is the major risk
2018-10-30
Smoking is the major risk factor for SCLC (Pesch et al., 2012; Engeland et al., 1996; Freedman et al., 2008). However, previous studies were limited in sample size and statistical power to estimate more precise effect size of smoking on SCLC risk as well as the non-linear exposure–response relations
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galanin br Introduction Tuberculous TB pericarditis
2018-10-30
Introduction Tuberculous (TB) pericarditis accounts for 50–70% of pericardial disease in Africa (Mayosi et al., 2005, 2006, 2008). Mortality rates range between 17 and 60% (Mayosi et al., 2008; Pusch et al., 2014; Shaw et al., 2010). The Investigation of the Management of Pericarditis (IMPI) regi
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Our results on the association between
2018-10-30
Our results on the association between PCBs and longer LTL are consistent with the findings reported by Shin and colleagues (Shin et al., 2010) in a cross-sectional study consisting of 84 healthy Korean individuals (33 men and 51 women) with a mean age of 56years (range 42–69years). The authors repo
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The most common risk factors associated with stroke eg heart
2018-10-30
The most common risk factors associated with stroke (eg, SGC707 failure, hypertension, diabetes, age, prior stroke) were initially identified from treatment naïve cohorts of randomised trials conducted 2 decades ago (Lip & Lane, 2015a). These trials only randomised 65 or in presence of an additiona
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One of the pivotal drugs in the
2018-10-30
One of the pivotal drugs in the regimen used to treat children with both drug-susceptible and MDR-TB, based on equivalent use in adults, is pyrazinamide (Donald et al., 2012). The doses for use in children are as yet unclear; based on computer aided clinical trial simulations we and others have prop
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On the basis of our genetic findings that hexokinase
2018-10-30
On the basis of our genetic findings that hexokinase 2 (HK2)-mediated aerobic glycolysis, known as the Warburg effect, drives prostate tumor growth in xenograft model bearing /p53-deficient murine or human prostate cancer YM155 (Wang et al., 2014), we designed preclinical studies to determine the t
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In early a serious ZIKV outbreak was recorded in
2018-10-30
In early 2015, a serious ZIKV outbreak was recorded in Camaçari, Bahia, Brazil (Plourde and Bloch, 2016; Cerbino-Neto et al., 2016) and this was later followed by similar illnesses in five neighboring states leading the Ministry of Health to issue a ZIKV alert in April (Rasmussen et al., 2016; Chan
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Another intriguing finding was that rs might
2018-10-29
Another intriguing finding was that rs12455792 might modulate the essential pathophysiological processes in TAAD-SMCs apoptosis, fibers accumulation and proteoglycans degradation, by fine tuning the SMAD4 expression. As we all known, the Dioscin is composed of 3 layers: tunica intima, tunica media
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thymidine phosphorylase br Acknowledgments C M O
2018-10-29
Acknowledgments C.M.O. holds thymidine phosphorylase Canada Research Chair in Metalloproteinase Proteomics and Systems Biology. J.H.C and A.E.S were supported by graduate fellowships from Natural Sciences and Engineering Research Council of Canada (NSERC), Canadian Institutes of Health Research (
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Kinematic data were low pass
2018-10-29
Kinematic data were low-pass filtered (15Hz cutoff; Matlab R2012a), ground reaction force data were low-pass filtered (50Hz cutoff), and internal joint moments were computed using matched filter cutoffs (15Hz). EMG data were band pass filtered (15–300Hz cutoff), full-wave rectified, and low-pass fil
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In this analysis the PCI values of less than
2018-10-29
In this analysis, the PCI values of less than 10 represent a uniform distribution of rainfall (i.e. low Lenalidomide concentration); the PCI values between 11 and 15 denote a moderate precipitation concentration; values from 16 to 20 denote irregular distribution and values above 20 represent a str
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Proceeding from previous work in adults Rossi
2018-10-29
Proceeding from previous work in adults (Rossi et al., 2011a, 2013) we here investigate how training impacts on phonotactic processing in 6-month-old infants. Specifically we ask to what extent establishing an associative link between novel objects and novel word-forms will modulate processing of tr
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In this analysis the optimized formulation A
2018-10-29
In this analysis, the optimized formulation A) F3, B) Guggul lipid, C) Phenylbutazone and D) Cholesterol were subjected to controlled temperature program in a controlled atmosphere. The combined TGA graph shown in (Fig. 4), that the TGA graph of pure drug showed that the mass remained constant with
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It is suggested that the analgesic effect of
2018-10-29
It is suggested that the analgesic effect of viscosupplementation may occur by blocking receptors and endogenous algic substances in the synovial tissues. A strictly mechanic mechanism by the interruption of trauma caused by mechanic block of the disk or of both adherence zones was also suggested [5
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The proposed techniques are used
2018-10-29
The proposed techniques are used for generating dependable rules from these datasets, and they alzheimer\'s disease also are employed for fixing errors found automatically to yield data into a consistent state. The cleaned data become on demand data access for decision making and management purposes
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