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Anti influenza agents are under development because
2018-10-23
Anti-influenza agents are under development, because antiviral therapy helps reduce the burden of seasonal influenza and provides the first line of defense against pandemic influenza before vaccines are available. Concerns regarding widespread resistance to M2 inhibitors and the emergence of NA inhi
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We profiled AR and MYC binding to
2018-10-23
We profiled AR and MYC binding to chromatin and found that they co-occupy circa one third of the binding sites. We performed RIME and immunoprecipitation experiments in order to comment on how MYC antagonises AR activity but we did not find evidences of direct interaction between the two transcripti
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Since Tnmd KO mice harbor very mild
2018-10-23
Since Tnmd KO mice harbor very mild developmental changes, including interesting ultrastructural phenotype characterized by irregular and thicker collagen I fibrils when examined by electron microscopy (Docheva et al., 2005), we hypothesized possible structural and biomechanical alterations of the t
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As for other described cross presentation events
2018-10-23
As for other described cross-presentation events depending on type I IFN, we can speculate that in the development of this mechanism, APC are able to generate an immune response against soluble EVP-6124 from invading pathogens. This will allow mounting a proper cellular killing arm of defense for n
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br Data Cross linking formaldehyde and denaturing ethanol
2018-10-23
Data Cross-linking (formaldehyde) and denaturing (70% ethanol and methanol/glacial acidic acid, 3:1, v/v) fixatives exert different effects on oocyte and NLB morphology (Fig. 1a, a′, a″), large-scale chromatin configuration (b, b′, b″) and on accessibility of the NLB material to immunofluorescenc
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br Experimental design materials and
2018-10-23
Experimental design, materials and methods X-ray diffraction datasets were collected at synchrotron beamlines ID23-1 [2] (ESRF) and XALOC [3] (ALBA), from flash cooled (in liquid nitrogen) single crystals and kept under nitrogen gas during data collection. Diffraction data already reduced and sca
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The flood prone areas maps have been
2018-10-23
The flood-prone areas maps have been derived applying a technique of pattern recognition through computational learning. Starting from morphological attributes of a basin, embodied in the Geomorphic Flood Index, a linear binary classifier was built and used to delineate flood-prone areas according t
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mm M projectile as shown in Fig a
2018-10-22
155 mm M549 projectile, as shown in Fig. 1(a), was used as an example in the present paper. The micro-vanes were mounted at the projectile shoulder to form a new physical model, as shown in Fig. 1(b). Fig. 2 shows the computational domain of M549 projectile. Fig. 2(a) shows the grid distribution of
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Si la transgresi n es un gesto que
2018-10-22
Si la transgresión es un gesto que concierne al límite, nuestros informantes ejecutan dicho gesto, pero retroceden al mismo tiempo. Salomón, tal vez el informante más disruptivo de los entrevistados, pide que los leathers sean vistos como hombres normales que exploran aspectos nuevos o distintos de
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Cirujana El cl toris ha sido estudiado y olvidado
2018-10-22
Cirujana: El clítoris ha sido estudiado y olvidado, descubierto y redescubierto por siglos. Pero no fue hasta 1998 cuando la uróloga australiana Helen O’Connell describió la anatomía completa del clítoris, por primera vez, hace apenas 16 años. Con ustedes “la madre del clítoris”. (Luz para rap) Dr
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during Planmeca AINO is enabled from Planmeca Romexis D
2018-10-22
Planmeca AINO™ is enabled from Planmeca Romexis® 3D image capturing dialog according to the patient case and diagnostic need. The software Analyses exposure data during reconstruction and adaptively differentiates noise and fine details. The original image is stored in the reconstruction PC (100 exp
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Then geographers and city planners joined
2018-10-22
Then geographers and city planners joined hands in developing studies on Chinese urbanization in China. Experts in city planning and authorities have taken the studies of urbanization as an important and long-term research field. After 1982, the City Planning Division of the State Ministry of Urban
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br Conclusions It is expressed in the sources
2018-10-22
Conclusions It is expressed in the sources that fortifications of Diyarbakir are approximately 5km long. However a solid measurement cannot be made. In this study solid measurements of the sections which are still standing and demolished sections (and also plan of all towers) are given. According
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In Flanders long lasting massive brick constructions are cha
2018-10-22
In Flanders long-lasting massive brick constructions are characteristic, especially within the housing market. Such houses own concrete floors installed in situ with raw materials or with prefabricated elements. The walls outside and inside are mostly brickwork. Outside walls are layered: inside wal
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order AZD-9291 br Research methodology The scope of this
2018-10-22
Research methodology The scope of this study focuses on evaluating the barriers and key factors that impede digital innovation adoption in different sizes of architectural organizations. Through the research questions mentioned in Section 1, six general variables (technological, financial, organi
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