• br Cardiac stem cell niches A challenging

  2018-11-08

  

  Cardiac stem cell niches: A challenging task The importance of the niche microenvironment for understanding HSC behavior was acknowledged shortly after the discovery of this adult stem cell class. In the absence of niches, the stemness of the primitive SR 3576 cannot be preserved. Outside of th

• Chemical library br Materials and methods br

  2018-11-08

  

  Materials and methods Author disclosure statement Acknowledgments We are grateful to Prof. Angel Raya for his help and advice with iPS cell generation. This work was supported by grants from the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER) (grant 13-717/132.05

• ikk pathway br Materials and methods br Acknowledgments We

  2018-11-08

  

  Materials and methods Acknowledgments We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the plasmids for reprogramming. We thank Bente Smith Thorup for excellent technical assistance in the cell culture. We thank Mehri Mirrajei for cytogenetic technical assistanc

• dub inhibitor Although there is strong clinical support for

  2018-11-08

  

  Although there is strong clinical support for developing cellular therapies, and the use of such therapies is already reaching clinical translation (Götherström et al., 2014), ethical issues associated with the collection and use of fetal tissue for research and therapy still remain. Concerned polit

• In our previous studies Choi

  2018-11-08

  

  In our previous studies (Choi et al., 2012; Vodyanik et al., 2006, 2010), we identified distinct stages of hematoendothelial development following hPSC differentiation in coculture with OP9 (Figure 1). Plating hPSCs onto OP9 stromal D-Luciferin induces the formation of primitive streak and mesoderm

• br Methods br Author contribution statement br Competing fin

  2018-11-08

  

  Methods Author contribution statement Competing financial interest Introduction Retinitis pigmentosa (RP) is just one of a group of heterogeneous inherited retinopathies and monogenic disorders that affect thousands of Americans and millions more worldwide (Daiger et al., 2013; Hamel, 20

• Our data are consistent with recent

  2018-11-08

  

  Our data are consistent with recent studies showing that in vivo, transplants of BM flap inhibitor were able to form bone and support marrow formation, while white adipose-derived stromal cells (WAT), cells from umbilical cord (UC), and skin fibroblasts (SF) were not (Kaltz et al., 2008; Reinisch e

• br Introduction Law also known as The Oil Law regulates

  2018-11-07

  

  Introduction Law 9478/97, also known as “The Oil Law,” regulates the collection and sharing of oil rents between the Brazilian federated entities. A significant portion of these rents is distributed to a subset of states and municipalities that must fulfill some requirements, like proximity to pr

• br Grant Support This work

  2018-11-07

  

  Grant Support This work was supported by a research grant from the National Science Council, Taiwan and the Institute of Biomedical Sciences, Academia Sinica (IBMS-CRC103-P02). Conflicts of Interest Author Contributions Introduction Because of late presentation and chemotherapy resistan

• TRAM 39 br Declaration of Interests br Author Contributions

  2018-11-07

  

  Declaration of Interests Author Contributions Acknowledgments This work was supported by the EU FP7 project TBIcare (Project ref. 270259; to M.O., D.M., and O.T.), by the GE-NFL Head Health Challenge I Award (grant no. 7620 to M.O. and T.H.), by personal EVO funding (Finland) (to J.P.P and

• HNP is the most abundant granule protein in neutrophils Whil

  2018-11-07

  

  HNP1 is the most abundant granule protein in neutrophils. While neutrophils have previously been found to be pro-atherogenic by instructing monocyte recruitment (Drechsler et al., 2010; Döring et al., 2012), the here presented data may seemingly suggest an opposite effect. However, rather than attri

• melanotropin cost The nuclear factor one NF family consists

  2018-11-07

  

  The nuclear factor one (NF1) family consists of four site-specific transcription factors (NfiA, NfiB, NfiC, and NfiX) that play a large role in the development of a number of organs systems such as the lung and melanotropin cost (Grunder et al., 2002; Harris et al., 2015; Hsu et al., 2011; Steele-P

• These findings must be interpreted

  2018-11-07

  

  These findings must be interpreted with limitations in mind. The study was a parallel group, longitudinal design typical for assessing treatment effects. However, the control group were healthy adolescents rather than patients randomized to placebo, due to ethical concerns of withholding treatment a

• Yang et al now show

  2018-11-07

  

  Yang et al. now show that fluvastatin inhibits lung cancer bone metastasis by triggering autophagy in lung cancer The impact of (). It was documented that fluvastatin inhibits migration and invasion by human lung cancer cells without significantly affecting proliferation and inhibits bone metastasi

• br Data sets and attributes The

  2018-11-07

  

  Data sets and attributes The data published here are organized in two ‘csv’ files, ‘rawdata.csv.gz’ (4.5MB) and ‘features.csv’ (200kB). The raw data are stored in the first file ‘rawdata.csv.gz’, where each line represents a single measurement per sensor. Consequently, one needs to read specific

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